Yeah, I've been messing around with the GT-R lately, putting together something fun now that I've got the Q right about where I want it.
Yes, your tuner has to make the adjustments, though you can have up to 4 maps. If you want boost by gear, you might have it on one of more maps, so you might have a 93 map, a 50/50 fuel map, an E85 boost by gear map, and an E85 track map with all the boost.
Ecutek has to compete with Cobb on the GT-R, and they've had 10 years to develop what they've got. I'm told there's some stuff in the works on the VR30, so I guess we'll just have to wait patiently.