Yes, you need to drop the motor to swap turbos. You also need upgraded injectors and both fuel pumps. If you have access to E85 consider the AMS flex fuel kit.
Be advised the Pure Stage 2 turbos, what I have, reduce torque at the low end. By a very noticable amount, but the top end is a huge advantage. It's a substantial trade off. Also, my MPG took a 2-3 MPG drop.
The power band is very similar to the VQ, but more power. 5K-7K (and beyond) is a HUGE difference. HOLD ON!!

LOL.
I now get the same or better MPG at 71-73 MPH than I do at 50-65 MPG unlike before. The OEM turbos loved 50-55 MPH giving me my best MPG.
So ECO mode now hurts my MPG. Standard mode gives me the best MPG of the modes. Because of these changes make sure you don't mind the negitive changes as it's VERY expensive to go back to OEM if you don't like them. So make sure you want to change your turbos.
I don't think the down sides are addressed enough. For me it was worth it. However, I do miss the low end torque "bump" of the OEM turbos.
Also, a substantial retune is needed. I peak at 24 PSI now, which is in the new efficiency range of the reworked turbos.